Skip to main content

It is one of the more strikin...

It is one of the more striking generalizations of biochemistry - which surprisingly is hardly ever mentioned in the biochemical textbooks - that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature.

Francis Crick 81 quotes

In my experience most mathema...

In my experience most mathematicians are intellectually lazy and especially dislike reading experimental papers. He seemed to have very strong biological intuitions but unfortunately of negative sign.

Francis Crick 81 quotes

One of the most frightening t...

One of the most frightening things in the Western world, and in this country in particular, is the number of people who believe in things that are scientifically false. If someone tells me that the earth is less than 10,000 years old, in my opinion he should see a psychiatrist.

Francis Crick 81 quotes

If Watson and I had not disco...

If Watson and I had not discovered the [DNA] structure, instead of being revealed with a flourish it would have trickled out and that its impact would have been far less. For this sort of reason Stent had argued that a scientific discovery is more akin to a work of art than is generally admitted. Style, he argues, is as important as content. I am not completely convinced by this argument, at least in this case.

Francis Crick 81 quotes

One can say, looking at the p...

One can say, looking at the papers in this symposium, that the elucidation of the genetic code is indeed a great achievement. It is, in a sense, the key to molecular biology because it shows how the great polymer languages, the nucleic acid language and the protein language, are linked together.

Francis Crick 81 quotes

Anybody who believes that the...

Anybody who believes that the earth is less than 10,000 years old needs psychiatric help.

Francis Crick 81 quotes

It is notoriously difficult t...

It is notoriously difficult to define the word living.

Francis Crick 81 quotes

When you start in science, yo...

When you start in science, you are brainwashed into believing how careful you must be, and how difficult it is to discover things. There's something that might be called the 'graduate student syndrome'; graduate students hardly believe they can make a discovery.

Francis Crick 81 quotes

A final proof of our ideas ca...

A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.

Francis Crick 81 quotes

How is the base sequence, div...

How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.

Francis Crick 81 quotes

A comparison between the trip...

A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement.

Francis Crick 81 quotes

It would appear that the numb...

It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.

Francis Crick 81 quotes

This seems highly likely, esp...

This seems highly likely, especially as it has been shown that in several systems mutations affecting the same amino acid are extremely near together on the genetic map.

Francis Crick 81 quotes

The balance of evidence both ...

The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.

Francis Crick 81 quotes

It seems likely that most if ...

It seems likely that most if not all the genetic information in any organism is carried by nucleic acid - usually by DNA, although certain small viruses use RNA as their genetic material.

Francis Crick 81 quotes

We are sometimes asked what t...

We are sometimes asked what the result would be if we put four +'s in one gene. To answer this my colleagues have recently put together not merely four but six +'s.

Francis Crick 81 quotes

It now seems certain that the...

It now seems certain that the amino acid sequence of any protein is determined by the sequence of bases in some region of a particular nucleic acid molecule.

Francis Crick 81 quotes

Attempts have been made from ...

Attempts have been made from a study of the changes produced by mutation to obtain the relative order of the bases within various triplets, but my own view is that these are premature until there is more extensive and more reliable data on the composition of the triplets.

Francis Crick 81 quotes

The meaning of this observati...

The meaning of this observation is unclear, but it raises the unfortunate possibility of ambiguous triplets; that is, triplets which may code more than one amino acid. However one would certainly expect such triplets to be in a minority.

Francis Crick 81 quotes

For simplicity one can think ...

For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the - class as having one too few.

Francis Crick 81 quotes

Добрые, щедрые, великодушные: 6 советских актеров, которые были всеобщими любимчиками

23

Советских актёров часто ставят в пример как образец духовной силы, национальной гордости и внутренней красоты. Они стали символами эпохи, носителями культуры и нравственности. Но, как известно, за кул...

Десять кинозвезд, которые отлично поют

83

Актеры — люди творческие, но кто бы мог подумать, что некоторые из них скрывают прекрасный голос. В эпоху раннего Голливуда актеров с музыкальными способностями было немало — это считалось скорее норм...

Мэрилин Монро, Ким Кардашьян и другие

115

Неузнаваемая Ким Кардашьян в объективе фотографа Маркуса Клинко, 2009 год. Памела Андерсон в самой первой съёмке для журнала «Playboy», 1990. На фото голливудская актриса Dorothy Lamour и шимпанзе Джи...

Что стало с детьми-звездами: Рэдклифф и компания спустя годы

219

Расскажем, как сложилась судьба актеров, которые начинали сниматься еще в детстве.
Остаться на вершине в Голливуде удаётся не каждому, особенно если путь начался в детстве. Одни актёры теряются из-за...

Жизнь за границей: как изменились судьбы 7 уехавших телеведущих

541

Два года назад отечественное телевидение столкнулось с беспрецедентной кадровой тектоникой — целая группа ярких и узнаваемых ведущих стремительно исчезла с экранов федеральных каналов. Эти лица долгие...

Кира Найтли, Деми Мур и другие

165

Кира Найтли на страницах журнала к выходу фильма «Пиджак», 2005. Следы динозавра, раскопанные в русле реки Палакси. Техас. США. 1952г. Самая большая женщина рядом с самым маленьким мужчиной, 1922 год....